Nick Foles, Eagles, had a rookie-record 32 completions while throwing for 381 yards and two touchdowns to help Philadelphia end an eight-game skid – the team’s longest in 42 years – with a 23-21 victory at Tampa Bay.
Philip Rivers, Chargers, threw three touchdown passes, two to Danario Alexander, in San Diego’s 34-24 win over Pittsburgh.
Eli Manning, Giants, threw four touchdown passes as New York cruised to a 52-27 rout of New Orleans.
Ben Roethlisberger, Steelers, completed 22 of 42 passes for 285 yards and three touchdowns in his first game back after spraining his right shoulder and dislocating a rib nearly a month ago.
Jamaal Charles, Chiefs, ran for 165 yards, breaking off an 80-yard TD run on the game’s first play for Kansas City, in a 30-7 loss at Cleveland.
Adrian Peterson, Vikings, rushed for 154 yards and two touchdowns to lead Minnesota to a 21-14 victory over the Chicago Bears.
Marshawn Lynch, Seahawks, had three touchdown runs ran for 128 yards on 11 carries in Seattle’s 58-0 win over Arizona.
Doug Martin, Buccaneers, rushed for 128 yards and a score in a losing cause.
Alfred Morris, Redskins, had 122 yards rushing and a TD on 23 carries as Washington edged Baltimore 31-28 in overtime.
Brandon Marshall, Bears, had 10 catches for 160 yards and a TD.
Kenny Britt, Titans, caught eight passes for 143 yards in a losing cause as Tennessee was edged 27-23 by Indianapolis.
Jason Avant, Eagles, had seven receptions for 133 yards.
Roddy White, Falcons, had nine catches for 117 yards and a touchdown, but Atlanta lost 30-20 at Carolina.
Mike Wallace, Steelers, caught two touchdown passes.
Bobby Wagner and Richard Sherman, Seahawks, each had two interceptions – Sherman returned one for a TD.
Aldon Smith, 49ers, had two sacks for an NFL-leading 19 1/2 , passing Fred Dean’s franchise-best single-season mark of 17 1/2 and within three of Michael Strahan’s seasonal NFL record set in 2001.
Cameron Wake, Dolphins, had three sacks.
Will Witherspoon, Panthers, ran an interception back 40 yards for a touchdown.
Harrison Smith, Vikings, returned an interception 56 yards for a score.
David Wilson, Giants, returned a kickoff 97 yards for one touchdown, ran for 100 yards and two more scores and piled up a team-record 327 all-purpose yards. He’s the first player in NFL history with 200 kickoff return yards and 100 yards rushing in the same game.
Dan Bailey, Cowboys, kicked a 40-yard field goal as time ran out, sending Dallas to a 20-19 victory over Cincinnati.
Travis Benjamin, Browns, had a 93-yard punt return for a touchdown – the longest in team history.
Phil Dawson, Browns, kicked field goals of 23, 24 and 34 yards and his first made him the 25th player in NFL history to make 300.