Andrew Luck, Colts, was 24 for 54 for 391 yards and four touchdown passes and three interceptions in Indianapolis 35-33 win over Detroit. Luck has 3,596 yards passing, the most by a rookie in his first 12 games. Lucks total already ranks third in NFL history for the most by a rookie in a single season, trailing Cam Newton (4,051) and Peyton Manning (3,739).
Russell Wilson, Seahawks, was 23 for 37 for 293 yards and two touchdowns in Seattles 23-17 overtime win over Chicago. Wilson has thrown a game-winning touchdown pass in the final two minutes of regulation or overtime three times. That is the most by a rookie since at least the 1970 merger.
Aaron Rodgers, Packers, was 27 for 35 for 286 yards with a touchdown and an interception in Green Bays 23-14 win over Minnesota.
Brandon Weeden, Browns, was 25 for 36 for a career-high 364 yards with a touchdown and two interceptions in Clevelands 20-17 win over Oakland.
Matthew Stafford, Lions, was 27 for 46 for 313 yards and two TDs and an interception.
Jamaal Charles, Chiefs, had 27 carries for 127 yards in Kansas Citys 27-21 win over Carolina.
BenJarvus Green-Ellis, Bengals, had 25 carries for 118 yards in Cincinnatis 20-13 win over San Diego.
Fred Jackson, Bills, had 25 carries for 109 yards in Buffalos 34-18 win over Jacksonville.
Shonn Greene, Jets, had 24 carries for 104 yards in New Yorks 7-6 win over Arizona.
Calvin Johnson, Lions, had 13 catches for 171 yards and a touchdownJohnson is the first player in NFL history with four consecutive games of at least 140 yards receiving in a season. He had at least 125 yards receiving for the fifth straight game.
Wes Welker, Patriots, had 12 catches for 103 yards and a touchdown in New Englands 23-16 win over Miami.
Brandon Myers, Raiders, had 14 receptions for 130 yards and a touchdown. He tied Tim Browns franchise record for catches in a game.
Brandon Marshall, Bears, had 10 catches for 165 yards.
Josh Gordon, Browns, had six receptions for 116 yards.
Steve Smith, Panthers, finished with five receptions for 120 yards.
Jason Hanson, Lions, was 4 for 4 on field goals.
Greg Zuerlein, Rams, made a 53-yard field goal at the end of the regulation and a 54-yarder in overtime in St. Louis 16-13 win over the 49ers.
Shaun Suisham, Steelers, made a 42-yard field goal as time expired to give Pittsburgh a 23-20 victory over Baltimore.
Morgan Burnett, Packers, had two interceptions.
Carlos Dunlap, Bengals, had two sacks, forced two fumbles (recovering one).
Whitney Mercilus, Texans, recovered a fumble and had two sacks in Houstons 24-10 win over Tennessee.
Demorrio Williams, Chargers, returned an interception 31 yards for a touchdown.
Von Miller, Broncos, returned an interception 26 yards for a touchdown in Denvers 31-23 win over Tampa Bay.
Janoris Jenkins, Rams, had a 2-yard fumble return for a touchdown. It was his third defensive score in two weeks.